Thursday, December 30, 2010

How does characterization reveal the inherent tension between illusion and reality in Hamlet?

The thin membrane separating illusion and reality in Shakespeare's Hamlet continues to enchant and beguile readers and audiences. Indeed, it's often difficult to know exactly what's real in Hamlet and what's fantasy. This tension is nowhere more apparent than in the characterization of Hamlet himself, especially in his decision to pretend to be "insane."


One of the central plot points in Hamlet is his "feigned" madness, put on originally to fool anyone who might otherwise catch on to his murderous plotting. Indeed, after talking with the ghost of his father during Act 1, Scene 5, Hamlet tells his friends to disregard him, no matter "how strange or odd some'er I bear myself -/ As I perchance hereafter shall think meet/ To put an antic disposition on -" (172). This quote suggests that Hamlet plans to purposefully pretend to be "antic," or crazy, in order to escape suspicion. 


All this is well and good, but as the play goes on, and as Hamlet's behavior becomes less and less effective and more and more outrageous, it's impossible not to wonder whether or not the prince is, in fact, actually mentally ill. As such, we begin to question the reality of his suspicions; perhaps, things regarding his mother, uncle, and father aren't exactly as they seem. After all, Hamlet was alone while talking to the ghost at the beginning of the play, and so it's possible some of the corruption in Denmark is a product of Hamlet's own diseased imagination, or perhaps the ghost itself is being dishonest. Now, Shakespeare makes no definitive statement either way on Hamlet's sanity, but the way that his character develops reveals the tension between reality and illusion; we're unsure whether or not Hamlet is sane or insane, and whether or not his suspicions are real or at least partially fabricated. It's one of the many ways that the play questions what's real and what's a product of our own illusions. 

Tuesday, December 28, 2010

What is smallpox?


Causes and Symptoms

The variola virus that causes smallpox is spread through physical contact with infected victims, sometimes through droplets from nasal or oral secretions and sometimes through contact with scabs carried on bedding, towels, clothing, or other fabrics. After exposure to the variola virus, the incubation period ranges from seven to seventeen days. Early symptoms resemble influenza and include headache, muscle ache, and sometimes vomiting. When the characteristic rash appears, the infected person is already seriously ill. In unvaccinated persons not treated with antiviral medications, between 20 and 40 percent of persons infected with classic smallpox (variola major) would be expected to die. Death most often occurs between the fifth and seventh day of illness.





The initial deep-seated rash characteristic of smallpox develops into lesions, which then follow a progressive sequence of fluid-filled vesicles, then pustules, and finally scabs. Lesions often appear first on the face. In contrast to chickenpox, in which “crops” of lesions appear, all smallpox lesions are at the same phase in development. Smallpox cases become contagious when the first lesions appear and remain so until the last scab separates from the skin. After the scabs are completely shed, the recovered smallpox victim is left with characteristic pitted scars over large portions of the body. Some victims are rendered permanently blind as a result of contracting smallpox; men may be left sterile. Survival is generally accompanied by lifetime immunity to further infections.




Treatment and Therapy

Smallpox may be prevented through vaccination. Live vaccinia virus is introduced into the skin tissue of healthy people in an effort to provide immunity against smallpox. The vaccinia virus is very similar to the variola virus that causes smallpox. Live vaccinia virus has been used for smallpox vaccinations since the time of Edward Jenner, the Englishman who pioneered vaccination in the late eighteenth century.


There is no treatment known to cure smallpox, although vaccination may be effective in lessening disease severity when administered within four days of exposure. In the 1970s, methisazone (N-methylisatin beta-thiosemicarbazone), trade name Marboran, was believed to afford some protection when administered early in the incubation period. Isolation of victims, burning all contaminated discharges, concurrent disinfection of the isolation environment, and sterilization of bedclothes and fabrics, combined with quarantine and vaccination of all persons susceptible to smallpox, has been used to contain epidemics in the historical past.


One of the last outbreaks of smallpox in the United States occurred in New York in 1947. To prevent a nationwide outbreak that year, the New York City Board of Health vaccinated about six million people (80 percent of the city’s population) within a four-week period.


The final smallpox outbreak in the United States occurred in the Rio Grande Valley of Texas in 1949. The last case reported in the Western Hemisphere was in Brazil in 1971. Prior to the official “last case” of smallpox observed in human populations in October 1977, international travelers were responsible for introducing the disease into areas where people had not received vaccinations to prevent smallpox. A laboratory accident in England in 1978 caused several cases of smallpox. In 1980, the World Health Organization (WHO) officially declared that smallpox had been eradicated. Major world powers, including the United States and the Soviet Union, maintained stocks of viable smallpox virus for further study.




Perspective and Prospects

There are no natural carriers of smallpox virus; prior to its eradication, it was an endemic urban disease found only in humans, spread as healthy people came into contact with smallpox cases or with fabrics containing scabs shed by smallpox patients.


Following the terrorist attacks on the United States on September 11, 2001, a series of letters containing anthrax spores were sent through the US mail. These letters caused inhalation anthrax, resulting in severe illnesses and several fatalities. Governments became concerned that terrorists would attempt to cause smallpox epidemics. Within the United States, a program was initiated in 2002 to vaccinate “first responder” health professionals in the event of a bioterrorist
attack using smallpox. Few people volunteered for vaccination, but among the outwardly healthy people who were vaccinated, two died unexpectedly from cardiovascular disease. News reports of these deaths made people who were offered vaccination less willing to participate, although subsequent study seemed to indicate that these deaths were not directly attributable to receiving the vaccine.


Few Americans, even those now involved in research on the smallpox virus, have ever seen an active case. If a bioterrorist attack using the smallpox virus were to occur, then medical personnel might have some initial difficulty identifying the disease. The general public would need to be informed about the disease in a manner that would avoid widespread panic and ensure that those exposed were immediately vaccinated and quarantined.


No medication has been approved to treat smallpox. Various antiviral agents had been investigated; the drug cidofovir (Vistide), at that time approved only to treat cytomegalovirus retinitis, was identified by several authorities as a potential agent to treat smallpox. Supportive measures that may be used include fever reducers, pain control medication, intravenous rehydration, and antibiotics to control secondary infections.


A single case of smallpox occurring anywhere in the world at any time in the future would constitute an immediate epidemiological emergency. Smallpox is a “Class 1” internationally quarantinable disease; any cases must be reported immediately to local, state, national, and international health authorities.


The resurgence of interest in smallpox at the start of the twenty-first century brought forth many new ideas about all aspects of the disease and its prevention. In 2003, several researchers noted that the increase in numbers of people infected by human immunodeficiency virus (HIV) corresponded with the decline in smallpox vaccinations worldwide. Laboratory research has since determined that prior infection with the vaccinia virus (through vaccination) may confer some immunity to HIV.




Bibliography:


Baciu, Alina, et al., eds. The Smallpox Vaccination Program: Public Health in an Age of Terrorism. Washington, D.C.: National Academies Press, 2005.



Benenson, Abram S., ed. Control of Communicable Diseases in Man. 16th ed. New York: American Public Health Association, 1995.



Division of Bioterrorism Preparedness and Response. "What You Should Know about a Smallpox Outbreak." Centers for Disease Control and Prevention, March 13, 2009.



Frieden, T., et al. “Cardiac Deaths After a Mass Smallpox Vaccination Campaign—New York City, 1947.” Morbidity and Mortality Weekly Report 52, no. 39 (October 3, 2003): 933–936.



Glynn, Ian, and Jenifer Glynn. The Life and Death of Smallpox. New York: Cambridge University Press, 2004.



Heymann, David L., ed. Control of Communicable Diseases Manual. 19th ed. Washington, D.C.: American Public Health Association, 2008.



"Smallpox." Health Library, December 30, 2011.



"Smallpox." National Institute of Allergy and Infectious Diseases, August 20, 2008.

In act I, Cyrano directly challenges three men. Who are they and why does Cyrano conflict with each?

Cyrano directly challenged De Valvert to a duel after De Valvert insulted him. Cyrano dueled with De Valvert after he attacked his character by stating that he was a buffoon. This was after De Valvert made an unpleasant comment about Cyrano’s nose. The two gentlemen engaged in a fencing duel while Cyrano recited a ballad as they fought.



CYRANO:


[with grimaces of pain] It must be moved—it's getting stiff! This is what happens when it's been unused for too long! Aie!


DE VALVERT:


What is the matter with you?


CYRANO:


The cramp! I have a cramp in my sword!


DE VALVERT:


[drawing his own sword] So be it!



A Bore came up to Cyrano admonishing him about stopping Montfleury from performing.  The Bore stated that Montfleury was protected by the Duke of Candal. Cyrano did not seem bothered about it, instead, he asserted that his sword was enough to protect him against anyone who challenged him. Cyrano challenged the Bore after he hesitated to leave at his request. He asked the Bore to tell him why he stared at his nose. The Bore was unable to explain himself and was forced to run away from Cyrano.



CYRANO:
Get out now! Go!
BORE:
But I—
CYRANO:
Go! Or tell me why you stare at my nose!
THE BORE:
[petrified] I—


CYRANO:



[walking straight up to him] Well, what's so strange about it?


Cyrano forced Montfleury off the stage and challenged him to return. Cyrano believed that Montfleury was a bad actor. He also had another reason but decided to keep it a secret. 



MONTFLEURY:


I—


CYRANO:


[leaves his chair, and settles himself in the middle of the circle which has formed] I will clap my hands three times, you full moon! On the third clap, I want to see you eclipse yourself! ...


CYRANO:


[delighted, sits back in his chair, arms crossed] Come back if you dare!....


A YOUNG MAN:


[to CYRANO] But, Sir, why do you hate Montfleury so much?


CYRANO:


[graciously, still seated] Young man, I have two reasons—either will suffice. First, he is a terrible actor. He heaves up his lines as though they were buckets of water drawn clumsily from a well, when instead, they should soar from his lips like the lightest of birds. The second reason …well, that's my secret.


Monday, December 27, 2010

What is Listeria?


Definition

The bacterium Listeria monocytogenes commonly contaminates
foods. It is difficult to detect and, in rare cases, causes listeriosis,
a serious and often fatal disease in humans.






Natural Habitat and Features


Listeria species are found in soil, decaying vegetation, water, sewage, and field crops such as alfalfa. The only pathogenic
species, L. monocytogenes, occurs in humans, other mammals,
birds, fish, crustaceans, and insects. L. monocytogenes also
occurs in foods such as vegetables, poultry, fresh and processed meats (such as
bologna and hot dogs), soft cheeses (such as feta, farmer’s cheese, and
queso blanco), and salad dressings. It occurs in raw foods and
in processed products. The first three confirmed outbreaks of listeriosis, in the
1980’s, were reported from ingesting coleslaw, milk, and Mexican-style cheese
(queso fresco), respectively.



Listeria spp. are characterized as gram-positive, non-spore-forming rods, which may occur in short chains or in coccoid forms. They are facultative anaerobes, are catalase-positive, always ferment, and ferment sugars to produce acid. Their cell walls contain teichoic acids but not mycolic acids. An unusual property of L. monocytogenes is that it can be intracellular in animal cells.



L. monocytogenes grows slowly under refrigerated conditions and
is resistant to cold, acid, and salt. These properties increase the risk of
infection from ingesting processed and stored foods that may
be contaminated.



L. innocua has a significantly larger genome than L. monocytogenes (3.01 megabases compared with 2.94 megabases), though L. innocua lacks some virulence genes and is nonpathogenic. Both genomes code for about 3,000 proteins, with perhaps 100 to 120 more in L. innocua. Thus, L. innocua grows in a wide variety of environments and is easier than L. monocytogenes to detect. Because of many genetic and metabolic similarities, and because they are often found together in a variety of situations, L. innocua could be used as an indicator of L. monocytogenes in quality control and regulatory analyses of foods. The two species grow slowly and indistinguishably on many laboratory media but can be distinguished by PCR (polymerase chain reaction) and colony morphology on special blood agars. Pulse-field gel electrophoresis of genomic deoxyribonucleic acid (DNA) and ribotyping are also used to distinguish Listeria spp.


Of the thirteen serovars of L. monocytogenes, listeriosis is most often caused by strains of just three: serovars 4b, 1/2a, and 1/2b. In the lab, serovars are distinguished by serotyping and phagetyping.




Pathogenicity and Clinical Significance

Even as a food-borne disease, listeriosis is not mainly a gastrointestinal
illness. Instead, severe symptoms include meningitis,
sepsis, and abortion in women in late-term pregnancy. Many people who ingest
L. monocytogenes do not show any symptoms but may carry
bacteria and act as a source of food contamination. The disease is especially
risky for infants, the elderly and bedridden, and persons with acquired immunodeficiency
syndrome (AIDS) or other immune disorders. Incidence of
listeriosis is about five cases per million people per year, probably worldwide.
Case fatality is quite severe at 20 to 30 percent. Thus, the United States reports
about five hundred deaths per year from listeriosis. Most cases are sporadic, and
epidemics are rare.


The virulence of L. monocytogenes is an inherent property of the bacterium because of virulence genes carried in its genome. After entering the gastrointestinal tract, bacteria are attacked by phagocytes but resist destruction. Instead, they persist intracellularly, proliferate inside phagocytes, and release progeny when phagocytes lyse, or break apart. The bacterial pore-forming protein listeriolysin O facilitates cell lysis of phagocytic cells. The bacterial surface protein internalin (InlA) aids in the crossing of the intestinal barrier to enter the nervous system. Other bacterial virulence proteins are InlB, ActA, PlcA, and PlcB. These proteins (with InlA and listeriolysin O) are encoded by virulence genes, some linked in a 10-kilobase region of the L. monocytogenes genome, absent from L. innocua.




Drug Susceptibility


Listeria spp. are susceptible to many different antibiotics,
though resistant strains are emerging. L. monocytogenes infection
in humans can usually be treated with ampicillin, especially if treatment starts
early. No vaccine is available.




Bibliography


Bell, Chris, and Alec Kyriakides. Listeria: A Practical Approach to the Organism and Its Control in Foods. 2d ed. Ames: Iowa State University Press, 2005.



Bibek, Ray, and Arun Bhunia. Fundamental Food Microbiology. 4th ed. Boca Raton, Fla.: CRC Press, 2007.



Doumith, Michel, et al. “New Aspects Regarding Evolution and Virulence of Listeria monocytogenes Revealed by Comparative Genomics and DNA Arrays.” Infection and Immunity 72 (2004): 1072-1083.



Glaser, Philippe, et al. “Comparative Genomics of Listeria Species.” Science 294 (2001): 849-852.



Montville, Thomas J., and Karl R. Matthews. Food Microbiology: An Introduction. 2d ed. Washington, D.C.: ASM Press, 2008.

Sunday, December 26, 2010

What is the connection between the French Revolution and the Haitian Revolution?

The Haitian Revolution was highly influenced by the exchange of culture and ideologies from the French mainland and the colonies France held. Prior to the Haitian Revolution, the island of Saint-Domingue was a French colony which produced coffee and sugar for export. Much like prior to the French Revolution, there was extreme class inequality in the colony of Saint-Domingue. Much of the population of the island were enslaved Black people who  had no control over their labor or life circumstance.


There were multiple motivations behind the Haitian Revolution, including the high tariffs on goods imported to the colony, and the ban on trade with any nation other than France. These were primarily the interests of the white plantation and slave-owners of the island, who made up a very small (but powerful) portion of society. Though the white upper class supported independence from France, the Mulatto and free and enslaved Black populations did not support a revolution lead by their white oppressors. An independence movement lead by the white plantation owners might result in worse treatment for the many People of Color who labored and lived on the island.


The French Declaration of the Rights of Man and of the Citizen, the key document of the French Revolution, brought the values of equality and freedom to French citizens- which now included the Jewish community and those who were previously enslaved. In the colonies, slavery persisted, and only white or Mulatto landowners were considered citizens. The spread of the values of the French Revolution, combined with legislative and societal inconsistency, came to a head in a number of slave revolts and the eventual defeat of French troops sent to quell the conflict. 


The Haitian Revolution is a dynamic event in history, not only for the aspect of national independence during the time of European colonialism, but also in the legacy of civil rights. Haiti became the first Black republic and is a real example of the needs of the many overpowering the wants of the few.

Saturday, December 25, 2010

How does Shakespeare portray masculinity in the Elizabethan age?

Shakespeare wrote during the Elizabethan and Jacobean eras, under Queen Elizabeth and King James. His plays depict a broad range of masculine expressions throughout many eras. His young men tend to be emotional and impetuous. Orlando in As You Like It moons over Rosalind and fights with his brother. Romeo falls for Juliet before becoming embroiled in a conflict and murdering Tybalt. Hamlet is yet another moody youth, who is alternately contemplative and rash.


There are also a number of patriarchal figures in Shakespeare’s plays. Prospero governs over his teenage daughter in The Tempest. He is both domineering and tender, seeking to control others but ultimately choosing forgiveness. Leontes in Winter’s Tale becomes overcome with suspicion and a masculine sense of paranoia about his wife and lineage before eventually coming to his senses and realizing his foolishness. King Lear becomes senile and ornery as he grows old, railing against his daughters and the world. Like Leontes, he has moments of clarity, finally admitting that he is “old and foolish,” simply “a very foolish fond old man.”


Another quality that Shakespeare examines is the connection between masculinity and violence. Coriolanus is about a man who, though controlled by his mother, exemplifies manly action. He becomes furious when his nemesis belittles him with the word “boy” and chafes at speaking sweetly to the despised commoners, connecting peace with femininity:



… my throat of war be turn'd,
Which quired with my drum, into a pipe
Small as an eunuch, or the virgin voice
That babies lulls asleep!



Both Macbeth and Othello sink into violence which they have learned from fighting bravely in war, a “manly” enterprise. Characters associate both Queen Margaret and Tamora in their respective plays with masculine and inhuman elements because of their brutality: “No grace? no womanhood? Ah, beastly creature!”


Obviously, masculinity in that era came in many shapes and sizes. Shakespeare portrayed men who were funny, pious, foolish, wicked--the list goes on. These are just a few examples of many studies on masculinity found in his plays.

Friday, December 24, 2010

What is the dominant impression of O'Connor's "A Good Man is Hard to Find?"

What may be considered a dominant impression is the grandmother's salvation at a most unsuspected moment, and it is a moment of violence, as well.


Flannery O'Connor herself has stated that she uses violence to grab readers' attention so that they will not miss the moment of grace. Added to this violence is the fact that in this Southern Gothic tale it is the grotesque, the Misfit, who recoils from the grandmother, rather than the other way around. This action, too, brings the readers' focus onto the unsuspected moment that the grandmother realizes that she is herself a sinner:



"...Why, you're one of my children!" ....She reached out and touched him on the shoulder. The Misfit sprang back as if a snake had bitten him and shot her three times through the chest.



After she is shot, the grandmother collapses into a seated position with her legs crossed before her, much like a Christ-figure who has been taken down from the crucifix. This Christian image, then, underscores the grandmother's salvation effected through violence.


The demonstration that this salvation of the grandmother is attained through violence are the words of the grotesque himself, "She would of been a good woman...if it had been somebody there to shoot her every minute of her life."

What is person-centered therapy (PCT)?


Introduction

Psychologist Carl R. Rogers
was the leading figure in the development of phenomenological therapy, and his name has been used synonymously (“Rogerian” therapy) with person-centered therapy (or client-centered therapy). Phenomenological theory is a method of exploration that emphasizes all aspects of human experience. In particular, it highlights the importance of an individual’s creative power, in addition to genetics and environment. Moreover, this theory focuses primarily on a person’s subjective experience (opinions, viewpoints, and understandings) and defines therapy on the basis of a good human-to-human relationship.







Rogers remained primarily concerned with the conditions for personal growth rather than with the development of personality theory; he focused on personality functioning rather than on personality structures. He did, however, offer formal conceptions of personality. The central concepts and key formulations of person-centered therapy were published in Rogers’s Counseling and Psychotherapy: Newer Concepts in Practice (1942), On Becoming a Person (1961), and his landmark book, Client-Centered Therapy (1951). Rogers presented nineteen propositions about personality development. These propositions included the following concepts: Each individual exists in a continually changing world in which he or she is the center. Individuals react to the world as they experience and perceive it; thus, “reality” is defined by the person’s phenomenal field. Behavior is basically the goal-directed attempt of the organism to satisfy its needs as experienced in the phenomenal field. Each individual has a unique perspective—his or her own private world—and to comprehend a person, one must assume a frame of reference from the person’s perspective. Emotion facilitates goal-directed behavior. The structure of the self is formed as a result of evaluative interactions with others; the self is an organized, fluid, yet consistent pattern of perceptions about oneself.


The phenomenal field refers to everything experienced by an individual at any given time. The term “internal frame of reference” refers to the process by which therapists attempt to perceive clients’ experiences and “reality” as closely as they can. An individual’s reality is essentially that which the person perceives. Moreover, it is the person’s subjective experience and perceptions that shape the person’s understanding of reality and guide behavior. Events are significant for an individual if the individual experiences them as meaningful. In treatment, therapists strive to understand clients by understanding their views of themselves and the environment in which they live.




Importance of Self

A central concept within phenomenological theory is the “self” (a structure derived from experiences involving one’s own body or resulting from one’s own actions). The self (or self-concept), then, is a self-picture or self-awareness. It is a changing process that incorporates the individual’s meaning when he or she refers to the characteristics of “I” or “me” in isolation or in relationships with others. The concept of self is also considered to be an organized, consistent, and learned attribute composed of thoughts about self. Rogers views the need for positive regard to be universal. The self-concept depends, in large part, on the “conditions of worth” that a child has learned through interactions with significant others. According to Rogers, the child’s need to maintain the love of parents inevitably results in conflict with his or her own needs and desires. For example, as young children assert greater autonomy, a growing awareness of individuality and uniqueness follows. Quite often, the young child demonstrates a negativistic pattern wherein conflicts become more common as the child’s needs are in conflict with parent desires.


Maladjustment occurs when there is a lack of consistency between one’s concept of self and one’s sensory and visceral experiences. If the self-concept is based on many conditions of worth and includes components of failure, imperfection, and weakness, then a lack of positive self-regard will be evident. When such incongruence occurs, individuals are viewed as being vulnerable to psychological problems. Of particular importance is self-esteem (feelings about self), which is often negative or problematic in clients. Poor self-esteem occurs when the phenomenal self is threatened. A threat for one person is not necessarily a threat for another. A person will experience threat whenever he or she perceives that the phenomenal self is in danger. For example, if a well-adjusted athlete misses the final shot at the buzzer in a close basketball game, he or she will not blame the referees or claim physical illness, but instead will examine this experience and perhaps revise his or her self-concept.




Self-Direction, Self-Actualization, and Congruence

Other key principles that underlie person-centered theory involve the processes of self-direction and self-actualization. According to Rogers, humans have an innate tendency to maintain and enhance the self. In fact, all needs can be summarized as the urge to enhance the phenomenal self. Although the process of self-actualization may become disrupted by a variety of social, interpersonal, and cultural factors (determined in large part by the actions of parents, teachers, and peers), Rogers states that the positive growth tendency will ultimately prevail. This actualizing tendency is what produces the forward movement of life, the primary force on which therapists rely heavily in therapy with clients. Self-actualization refers to the concept that unhampered individuals strive to actualize, enhance, and reach their full potential.


Via self-actualization, a person becomes a fully functioning individual. The qualities of a fully functioning person include being open to experience all feelings while being afraid of none; demonstrating creativity and individual expression; living in the present without preoccupation with past or future; being free to make choices and act on those choices spontaneously; trusting oneself and human nature; having an internal source of evaluation; demonstrating balance and realistic expressions of anger, aggression, and affection; exhibiting congruence between one’s feelings and experience; and showing a willingness to continue to grow.


Congruence is the term used by Rogers and others to imply the correspondence between awareness and experience. If a client is able to communicate an awareness of feelings that he or she is currently experiencing, the behavior is said to be congruent or integrated. On the other hand, if an individual attempts to communicate a feeling (love, for example) to another person while experiencing incongruence (hostility toward that person), the recipient of that individual’s expression of feelings may experience an awareness of miscommunication.




Evolution of Study

Person-centered theory and therapy have evolved since the 1940s. When Rogers published Counseling and Psychotherapy, the predominant view among mental health professionals was that the therapist should act as an expert who directs the course of treatment. Rogers, however, described counseling as a relationship in which warmth, responsiveness, and freedom from coercion and pressure (including pressure from the therapist) are essential. Such an approach to treatment emphasized the client’s ability to take positive steps toward personal growth. This phase, from 1940 to 1950, has been called Rogers’s nondirective period. The second phase, reflective psychotherapy, spanned the years from 1950 to 1957. During this period, Rogers changed the name of his approach to “client-centered counseling” and emphasized the importance of reflecting (paraphrasing, summarizing, and clarifying) the client’s underlying feelings.


The third phase, experiential psychotherapy, has been described as lasting from 1957 to 1970. During this phase, Rogers focused on the conditions that would be necessary and sufficient for change to occur. Results of his studies demonstrated that the most successful clients were those who experienced the highest degree of accurate empathy, and that client ratings, rather than therapist ratings, of the quality of the therapeutic relationship were most closely associated with eventual success or failure. Also evident during this phase of development was Rogers’s deemphasis of psychotherapy techniques, such as reflection. Instead, he focused more on the importance of basic therapist attitudes. By so doing, he encouraged a wider range of therapist behaviors to establish the essential relationship components of empathy, positive regard, and congruence. Therapists were encouraged to attend to their own experiences in the session and express their immediate feelings in the therapy relationship.


In 1974, Rogers changed the name of his approach to person-centered therapy. Rogers believed that person-centered therapy more appropriately described the human values that his approach incorporates. Since the 1970s, an additional phase of person-centered therapy, incorporating a more eclectic approach to treatment, has evolved. Specifically, person-centered therapists frequently employ strategies that focus on thoughts, feelings, and values from other schools of psychotherapy within the framework of a productive, accepting relationship. Person-centered approaches have been successfully incorporated into teaching and educational curricula, marriage programs, and international conflict-resolution situations.




Therapeutic Relationships

Person-centered therapy aims to increase the congruence, or matching, between self-concept and organismic experience. As Rogers described it, psychotherapy serves to “free up” the already existing capacity in a potentially competent individual, rather than consisting of the expert manipulation of techniques designed to change personality. The primary mechanism for reintegration of self and experience is the interpersonal relationship between therapist and client. In fact, the therapeutic relationship is viewed as being of primary importance in promoting healing and growth. Thus, it is this relationship in and of itself that produces growth in the client. Rogers argues that the process of therapy is synonymous with the experiential relationship between client and therapist; change occurs primarily as a result of the interaction between them.


As described by N. J. Raskin and Rogers in 1989, the most fundamental concept in person-centered therapy is trust—that is, trust in clients’ tendency to grow toward actualization and trust in clients’ ability to achieve their goals and run their lives. Similarly, it is important that the therapist be seen as a person in the relationship (not as a role), and that the therapist be appreciated and regarded with trust. Rogers stated that clients enter treatment in a state of incongruence, often resulting in vulnerability and anxiety. For treatment to be effective, he identified three necessary and sufficient ingredients for constructive change: The counselor experiences empathic understanding of the client’s internal frame of reference, the counselor experiences unconditional positive regard for the client, and the counselor acts congruently with his or her own experience, becoming genuinely integrated into the relationship with the client. It is also essential to the therapy process that the counselor succeed in communicating unconditional positive regard, genuineness, and empathic understanding to the client.


Of particular importance is empathy. Empathy reflects an attitude of interest in the client’s thoughts, feelings, and experiences. Moreover, Rogers describes empathy as “a way of being” that is powerfully curative because of its nonevaluative and accepting quality. In fact, the process of conveying accurate empathic understanding has been described as the most important aspect of the therapeutic endeavor. Therapists who convey this form of sensitivity to the needs, feelings, and circumstances of the client can in essence climb inside the client’s subjective experience and attempt to understand the world as he or she does. Empathy facilitates a process through which clients assume a caring attitude toward themselves. Moreover, empathy allows clients to gain a greater understanding of their own organismic experiencing, which in turn facilitates positive self-regard and a more accurate self-concept.


In perhaps all of their previous relationships, clients have learned that acceptance is conditional on acting in an acceptable manner. For example, parents typically accept children if they do as they are told. In therapy, however, Rogers argued that no conditions of worth should be present. Acceptance of the client as a fallible yet essentially trustworthy individual is given without ulterior motives, hidden causes, or subtle disclaimers. The primary challenge of the therapist’s unconditional positive regard comes with clients whose behavior and attitude run strongly counter to the therapist’s beliefs. A sex offender, an abusive parent, or a lazy client can test a therapist’s level of tolerance and acceptance. Rogers’s position is that every individual is worthy of unconditional positive regard.


Genuineness refers to the characteristic of being congruent—the experience of therapists who appropriately express the behavior, feelings, and attitudes that the client stimulates in them. For example, a person does not laugh when sad or angry. Similarly, acting congruently with one’s own emotional experience does not mean hiding behind a mask of calm when a client makes upsetting statements. Rogers believed that, in the long run, clients would respond best to a “real person” who is dedicated to the client’s welfare and acts in an honest and congruent manner.




Seven Steps of Therapy

In person-centered treatment, sessions are usually scheduled once or twice a week. Additional sessions and telephone calls are typically discouraged to avoid dependency on the therapist that will stifle personal growth. Rogers has described the general process of therapy as involving a series of seven steps. Step one is an initial unwillingness to reveal self and an avoidance of feelings; close relationships may be perceived as threatening or dangerous. In step two, feelings are described briefly, but the person is still distant from his or her own personal experience and externalizes issues; the person begins to show recognition that conflicts and difficulties exist. In step three, describing past feelings becomes unacceptable; there is more self-disclosure and expression, and the client begins to question the validity of his or her constructs and beliefs.


Step four involves the description of personal feelings as owned by the self and a limited recognition that previously denied feelings may exist; there is an increasing expression of self-responsibility. Step five involves the free expression and acceptance of one’s feelings, an awareness of previously denied feelings, a recognition of conflicts between intellectual and emotional processes, and a desire to be who one really is. In step six, there is an acceptance of feelings without the need for denial and a willingness to risk being oneself in relationships with others. In step seven, the person is comfortable with his or her self, is aware of new feelings and experiences, and experiences minimal incongruence.




Influences

As Rogers began his career during the late 1930s, psychoanalysis was the primary approach to psychotherapy and the dominant model in personality theory. Though Rogers was subjected to traditional psychoanalytic influences, his perspective was nearly the exact opposite of Sigmund Freud’s theory; Rogers tended to reject the notion of unconscious processes. Instead, he was strongly influenced by the therapeutic approach of psychoanalyst Otto Rank
(and his followers at the University of Pennsylvania School of Social Work), the relationship therapy of social worker Jessie Taft, and the feeling-focused approach of social worker Elizabeth Davis. Rank believed that clients benefit from the opportunity to express themselves in session, exhibit creativity in treatment, and even dominate the therapist. Taft emphasized that there are key components to the therapeutic relationship (including a permissive therapeutic environment and a positive working relationship between the therapist and client) that are more important than psychoanalytic explanations of the client’s problems. Davis focused almost exclusively on the feelings being expressed in treatment by her clients. From his association with Davis, Rogers developed the therapy component referred to as reflection of feelings. Rogers believed strongly that no individual has the right to run another person’s life. Thus, his therapeutic approach was generally permissive and accepting, and he generally refused to give advice to clients.




Contributions to Psychology

Person-centered approaches have made major contributions to therapy, theory, and empirical research. In fact, Rogers was responsible for the first systematic investigations of the therapeutic process. He was the first to employ recordings of therapy sessions to study the interactive process and to investigate its effectiveness. Although the use of such recordings is now commonplace in most training programs, Rogers’s willingness to open his approach to such scrutiny was unusual for its time.


Person-centered therapy has generated numerous research contributions. A 1971 review of research on “necessary and sufficient” conditions concluded that counselors who are accurately empathic, genuine, and nonpossessively warm tend to be effective with a broad spectrum of clients regardless of the counselors’ training or theoretical orientation. The authors also concluded that clients receiving low levels of such conditions in treatment showed deterioration. Many researchers have questioned the “necessary and sufficient” argument proposed by Rogers, however; they suggest that the therapeutic conditions specified by Rogers are neither necessary nor sufficient, although such therapeutic approaches are facilitative.


Although Rogers’s approach was developed primarily for counseling clients, the person-centered approach has found many other applications. Person-centered approaches are frequently used in human relations training, including paraprofessional counselors, YWCA-YMCA volunteers, crisis center volunteers, Peace Corps and VISTA workers, and charitable organization workers. Small group therapy programs and personal growth groups also make frequent use of person-centered approaches.




Bibliography


Bazzano, Manu. "One More Step: From Person-Centered to Eco-Centered Therapy." Person-Centered & Experiential Psychotherapies 12.4 (2013): 344–54. Print.



Joseph, Stephen, and David Murphy. "Person-Centered Approach, Positive Psychology, and Relational Helping: Building Bridges." Journ. of Humanistic Psychology 53.1 (2013): 26–51. Print.



Kirschenbaum, Howard. Life and Work of Carl Rogers. Alexandria: American Counseling Association, 2009. Print.



Prouty, Gary. Theoretical Evolutions in Person-Centered/Existential Therapy. Westport: Praeger, 1994. Print.



Raskin, N. J., and Carl R. Rogers. “Person-Centered Therapy.” Current Psychotherapies. Ed. Raymond J. Corsini and Danny Wedding. 4th ed. Itasca: Peacock, 1989. Print.



Rogers, Carl R. Client-Centered Therapy. 1951. Reprint. Boston: Houghton, 1965. Print.



Rogers, Carl R. Counseling and Psychotherapy: Newer Concepts in Practice. 1942. Reprint. Boston: Houghton, 1960. Print.



Rogers, Carl R. On Becoming a Person. Boston: Houghton, 1995. Print.



Rogers, Carl R. A Way of Being. Boston: Houghton, 1995. Print.



Smyth, David. Person-Centered Therapy with Children and Young People: A Child-Centered Approach. London: Sage, 2013. Print.



Thorne, Brian. Carl Rogers. 2d ed. Thousand Oaks: Sage, 2003. Print.



Thorne, Brian, and Elke Lambers, eds. Person-Centered Therapy: A European Perspective. Thousand Oaks: Sage, 1998. Print.

What is onchocerciasis?


Definition

Onchocerciasis is a parasitic infestation by filarial worms (
Onchocerca volvulus) that affects persons in Africa, Latin America, and the Arabian Peninsula. Worm larvae enter the body from black-fly bites, causing nodular skin swelling that may progress to a harmful eye disease known as river blindness. Almost one-half of the adult population in the West African savanna has some visual impairment caused by onchocerciasis, the second-leading infectious cause of blindness worldwide.
















Causes

Black flies (genus
Simulium) feed on the blood of infected people and ingest microfilariae, the embryos of worms, which then mature into larvae in the gut of the fly within seven days. The larvae are then deposited into other persons through fly saliva. The larvae develop into adult worms then live and reproduce in firm nodules in the subcutaneous and deeper layers of skin. Adult worms produce numerous microfilariae, which travel from the parent nodule and move throughout the skin. The presence of the microfilariae, dead and alive, causes the body to have a powerful immune response, leading to a severe inflammatory reaction that damages surrounding skin and eye tissue.




Risk Factors

Persons who live in Africa, Latin America, and the Arabian Peninsula near
streams and rivers, the breeding habitat for the black fly, are at the greatest
risk for developing onchocerciasis.




Symptoms

Symptoms of onchocerciasis may not appear until three to fifteen months after
infection. Early indicators include skin nodules that contain two or more adult
worms. The migration of microfilariae causes a severe rash and painful, hot, or
swollen skin. Lymph nodes in the neck and groin can become enlarged. Chronic
infection may lead to thickened, pigmented, or depigmented skin, often in a lizard
or leopard pattern. If the microfilariae migrate to the eye, the body’s
immune
system responds by destroying the eye tissue, leading to
deteriorating vision. People who have been infected with only a few larvae may not
experience any noticeable symptoms at all.




Screening and Diagnosis

Diagnosis of onchocerciasis is commonly made by analysis of skin snips that
contain microfilariae or by excision of the nodule containing adult worms. A
dipstick test for the presence of an antigen in urine or tears has been
developed; however, results do not distinguish between current and past
infection.




Treatment and Therapy

In 1986, the World Health Organization (WHO) worked collaboratively with
pharmaceutical company Merck to develop ivermectin, the most effective treatment
for onchocerciasis. Ivermectin is administered in two doses, six months apart,
every three years. Community directed treatment programs have been established to
provide treatment at no cost. Damage done to skin and eyes cannot be reversed, but
treatment prevents further deterioration by killing the microfilariae. Although
treatment does not kill the adult worms, it prevents them from reproducing.




Prevention and Outcomes

WHO has initiated the several prevention programs, including the Onchocerciasis
Control Programme, the African Programme for Onchocerciasis Control, and the
Onchocerciasis Elimination Program for the Americas. Preventive measures by these
programs include spraying of insecticides to prevent black-fly
breeding in affected areas and distributing ivermectin treatment to persons and
communities in need.




Bibliography


Stingl, Peter. “Onchocerciasis: Developments in Diagnosis, Treatment, and Control.” International Journal of Dermatology 48 (2009): 393-396.



Taylor, Mark, et al. “Lymphatic Filariasis and Onchocerciasis.” The Lancet 376 (2010): 1175-1185.



World Health Organization. Special Programme for Research and Training in Tropical Diseases. “Eliminating River Blindness.” Available at http://www.who.int/tdrold/publications/publications/ elimin_riverblind.htm.

What passage identifies the author's purpose in Warriors Don't Cry?

One passage that identifies Melba Pattillo Beals's purpose in the book Warriors Don't Cry is the following:



"My eight friends and I paid for the integration of Central High with our innocence...The physical and psychological punishment we endured profoundly affected all our lives. It transformed us into warriors who dared not cry even when we suffered intolerable pain" (page 2).



Her purpose is to show the immense pain and humiliation that the Little Rock Nine suffered as they attempted to integrate Central High School. They responded to the harassment at the hands of white students by reacting with stoicism, meaning that they did not feel that they could react with fear or anger. As a result, they became warriors that were not able to show pain. Their natural human emotions in the face of a great deal of pain were suppressed, and they suffered as a result. They grew up quickly and lost any sense of being innocent children.

Describe the old man that is found on the beach in "A Very Old Man with Enormous Wings."

Besides his huge buzzard wings and his apparent age, as evinced by a bald skull with only a few hairs and missing teeth in his mouth, the creature who lands in Pelayo and Elisenda's yard after days of rain defies real description.


With its subtitle of "A Tale for Children," Marquez's story, whose fictional landscape challenges traditional modes of fiction with its magical realism, seems to beckon readers to employ their imaginations in their reading of his tale. Certainly, this employment of imagination is what the characters exhibit as they first view this strange creature.


  • Here are the characters' different perceptions of the old man with enormous wings:

--Pelayo and Elizabeth, who look so long at the old man that he becomes "familiar to them," decide after hearing him speak in some "incomprehensible dialect" that he is a castaway from some foreign ship wrecked by a storm.
--A neighbor woman "who knew everything about life and death" dogmatically declares that Pelayo and Elizabeth are wrong. She insists that the old man is an angel knocked down by so much rain.
--Other neighbors feel that the old man with enormous wings is a "fugitive survivor of a celestial conspiracy" and want to club him to death.
--Rather simple-minded people think he should be named mayor.
--Others of "sterner mind" feel that he should be promoted to five-star general.
--The local priest, Father Gonzaga, decides that the old man is definitely not an angel, and he is much too human because he has parasites in his main feathers and a smell of the outdoors; in short, he does not measure up to the "proud dignity" of angels. Moreover, he does not understand Latin, the "language of God."
--The doctor who treats the child is amazed at the logic of the old man's enormous wings. They seem so natural that he wonders why others do not have such wings.


From these various judgments of the bizarre creature who lands in the yard of Pelayo and Elizabeth, an understanding comes to readers as to why Marquez subtitles his story "A Tale for Children." Certainly, the various characters exhibit a childlike point of view toward the old man with enormous wings and the events that they witness, interpreting them in accord with their own limited imaginations.

Thursday, December 23, 2010

If a person has to remove one kidney, or is an organ donor, what are the side effects of only having one kidney?

There are a number of reasons someone might live with just one kidney, including the reasons you mentioned. Donation and removal due to illness aren't the only reasons someone might live with just one kidney, though. In fact, about one in every seven-hundred and fifty people is born missing one of their kidneys! It is possible to live a long, healthy life with just one kidney, but a person in this condition must be careful not to put too much strain on the extant kidney.


People with just one kidney are at a higher risk for high blood pressure. This may require medication in some cases. Additionally, because just one kidney is performing a job typically done by two, a person may have trouble filtering metabolic waste from their blood stream. This can result in kidney disease if the levels of waste in the blood are too high. Some people may also develop a condition called proteinuria where too much protein is taken from the blood and expelled through urine. An imbalance like this can cause edema or fluid retention in the body.


Long term, someone who lives with just one kidney might experience a decrease in kidney function due to the amount of work this kidney has to do. Eating a balanced diet and drinking lots of water helps to maintain the appropriate levels of water and nutrients in the blood and can help prevent kidney disease. It is also important for people with a single kidney to protect it if they choose to play sports, so as not to damage the organ. 

How are innocence and guilt paired in A Separate Peace?

In many ways A Separate Peace is about the loss of innocence through Gene's actions against Finny, which naturally cause a great deal of guilt within him. It's a coming of age story, and as Gene transitions into adulthood, he carries the weight of evil actions with him. Gene's guilt is actually omnipresent throughout the latter 2/3 of the novel, and on multiple occasions Gene tries to tell Finny what he did at the tree, when he jounced the limb and caused Finny to fall and break his leg. Gene's guilt is a direct result of that loss of innocence, of that selfish, impulsive action he took against his best friend, who had no ill motives toward him despite the fact that Gene (incorrectly) perceived that he did. The relationship in the novel is representative of the greater narrative of WWII, in which countries fail to listen to and understand one another, and fight as a result. 

What natural phenomena occurs in the poem "To His Excellency General Washington" by Phyllis Wheatley?

In the third stanza of the poem, Wheatley begins to relate natural phenomena to the army's movement under the leadership of General George Washington. She writes,



Muse! Bow propitious while my pen relates


How pour her armies through a thousand gates,


As when Eolus heaven’s fair face deforms,


Enwrapp’d in tempest and a night of storms;


Astonish’d ocean feels the wild uproar,


The refluent surges beat the sounding shore;


Or think as leaves in Autumn’s golden reign,


Such, and so many, moves the warrior’s train (lines 13-20).



First, Wheatley invokes the Muse to aid her in recounting the tales of the armies. She compares the army to the god of the wind, Eolus, who creates tempests and storms and churns up the ocean with his might. She then compares the army to autumn leaves by saying the number of leaves that fall from the trees is the same number of warriors marching to victory.


Wheatley uses these natural phenomena to create a concrete image for her readers of the victories of the American army under General Washington. She sings his praises throughout, comparing Washington to the gods that she references.

How would you describe the contrasts in Othello and Iago's perceptions of love?

Iago and Othello seem to possess contrasting ideas of love. One can interpret each man's thoughts on love from his associations with others, and, more pertinently, from his relationship with his wife.


In Act I, it is clear Iago sees (what he believes to be) love as a tool to be used when manipulating others. He has a cynical understanding of the term. When Iago first uses the word 'love,' he expresses its negative connotation. He tells Roderigo in Act I, scene 1:



...But he; as loving his own pride and purposes,... 



In this instance, Iago criticizes Othello's love for himself and his ambitions, suggesting the general is displaying a boastful pride in his own status and future aspirations. Such a love is selfish and self-serving. Iago also states that he would show love to the general insofar as it serves his own purpose. The love Iago speaks of is not real, but part of an act. He says,



...not I for love and duty,
But seeming so, for my peculiar end:...



Iago later appeals to Brabantio's love for his daughter as a means to urge him to take action against Othello, who, Iago and Roderigo claim, has abducted her. 



'Zounds, sir, you're robb'd; for shame, put on
your gown;
Your heart is burst, you have lost half your soul;
Even now, now, very now, an old black ram
Is topping your white ewe.



After the two demonize Othello in Brabantio's eyes, Iago leaves to be with the general for, as he puts it:



I must show out a flag and sign of love,
Which is indeed but sign.



Iago has to create the impression that he supports Othello out of love and will stand by him against Brabantio's accusations. It is all just a show, as Iago actually despises Othello. In Scene 3 of Act 1, Iago reveals his true feelings about what he believes love to be when the lovesick Roderigo expresses his desire to drown himself since Desdemona will be leaving for Cyprus with Othello:



...but we have
reason to cool our raging motions, our carnal
stings, our unbitted lusts, whereof I take this that
you call love to be a sect or scion.


It is merely a lust of the blood and a permission of
the will.



Iago deems love to be merely a feeling of lust and desire. It is a curse and meaningless persuasion of the body, not the heart. Iago later expresses the same kind of sentiment when he talks about Desdemona's love for Othello and says that if she had been blessed she would never have loved him, implying that her so-called love is actually lust.


In his monologue later, Iago says he loves Desdemona, not out of lust but because his supposed 'love' serves a different purpose:



...Now, I do love her too;
Not out of absolute lust, though peradventure
I stand accountant for as great a sin,
But partly led to diet my revenge,...



There are a number of instances in which Iago expresses his love for Othello, but this is merely part of his plot to manipulate the general and win his trust. Iago is entirely convincing and Othello becomes completely ensnared by his web of lies. Further evidence of Iago's inability to love can be found in the fact that he never expresses any soft sentiment towards Emilia, his wife. He does, however, abuse her love for him to get what he wants, such as Desdemona's precious napkin.


In contrast, Othello seems to be a genuine disciple of love. He states as much when he explains what led to his and Desdemona's elopement in Act 1, Scene 3:



...I will a round unvarnish'd tale deliver
Of my whole course of love; what drugs, what charms,
What conjuration and what mighty magic,
For such proceeding I am charged withal,
I won his daughter.


...She loved me for the dangers I had pass'd,
And I loved her that she did pity them.



We know that Othello has real feelings for Desdemona because he continuously expresses his love. Upon his arrival in Cyprus, Othello says the following when he sees his wife:



It gives me wonder great as my content
To see you here before me. O my soul's joy!



He constantly uses terms of endearment such as "sweeting," "love," "dear love," and "chuck." It is clear Othello dotes on Desdemona and is a devoted husband.    


It is the cynical and malicious Iago who taints the purity of Othello's love. His insidious lies and manipulation drive the general insane with jealousy, so much so that he falls into a fit, rejects Desdemona's advances and, at one point, slaps her in public. When he decides to suffocate Desdemona, his anguish is quite clear, for he still loves her. He approaches her while she is still sleeping and repeatedly kisses her, saying in Act 5, Scene 2:



Ah balmy breath, that dost almost persuade
Justice to break her sword! One more, one more.
Be thus when thou art dead, and I will kill thee,
And love thee after. One more, and this the last:
So sweet was ne'er so fatal. I must weep,
But they are cruel tears: this sorrow's heavenly;
It strikes where it doth love.



When Othello later realizes his actions were borne from Iago's malice, he cannot forgive himself and, filled with remorse and regret, commits suicide.


It is clear Othello and the amoral Iago have entirely different perspectives on what it is to love. Iago clearly sees it as a weakness which can be exploited whilst Othello, who has been genuinely touched by love, forfeits it by foolishly succumbing to a greater weakness—insecurity. Both these sentiments are ruthlessly exploited by the malevolent Iago.

Why are Jonas and his father worried about Gabriel's fretfulness at night, and how did Jonas try to solve the problem in The Giver?

Both his father and Jonas are concerned that Gabriel is fretful at night because sleeping through the night is required of the new children. If the newchild continues to not sleep well at night, he will be released.


Dispassionately, Jonas's father tells the family in their "evening telling of feelings" that it is rare that the status of a newchild such as Gabriel would be so uncertain. But, he adds,



"Right now we're all preparing for a Release we'll probably have to make soon."



Alarmed by these words of his father, Jonas suggests that the baby's crib be moved into his room for the night. He tells his parents that since he knows how to feed and comfort Gabriel, the parents could get a good night's rest by letting him care for Gabriel. Worried that Jonas is such a sound sleeper, his father is reluctant to do this. But, when Lily points out that Gabriel cries so loudly that even Jonas will awaken, Father agrees to "...try it, just for tonight."


When Gabriel awakens in the middle of the night, Jonas hears him and goes to his crib. He is able to get the baby back to sleep by rubbing his back. However, Gabriel continues to stir and awaken throughout the night; so, Jonas continues his rubbing of the infant's back to get Gabriel to fall asleep. One time, as he stands quietly beside the crib, Jonas's memory is stirred, and he recalls a memory shared with him by the Giver:



...a bright, breezy day on a clear turquoise lake, and above him the white sail of the boat billowing as he moved along in the brisk wind.



Then, as Jonas recalls this memory, he feels it slide through the hand he has on the back of the baby. Startled, he quickly removes his hand, retrieving what he has left of the memory. But now, the baby sleeps well. When he stirs near dawn, Jonas impulsively decides to give Gabriel the remainder of the memory by placing his hand once more on the baby's back.


By giving Gabriel a memory, Jonas has taken a personal action for which he has no authority:



He was not yet qualified to be a Giver himself, nor had Gabriel been selected to be Receiver.



Frightened by his new power, Jonas decides to keep his act of sharing his memory with Gabriel a secret. There is also in Jonas a burgeoning feeling of anxiety about the conditions that exist in his society. For, he wonders about Elsewhere and how easily his parents speak of this place where Gabriel may be sent. Also, Jonas is concerned about the fact that his father mentions so dispassionately that if Gabriel is released, there is another set of twins due to be born very soon. When his father will be the one to select which one will live in the community and which one will be released, Jonas feels uneasiness, as well as wondering where these human beings all go.

Tuesday, December 21, 2010

In what two ways does Hamlet disobey the ghost?

When old King Hamlet's ghost speaks with the prince, his son, he charges the prince with the task of avenging his murder.  This means, really, that young Hamlet will likely have to kill the new king, Claudius, his uncle and now step-father.  Old Hamlet's ghost also instructs him, saying,



"howsoever thou pursuest this act, / Taint not thy mind, nor let thy soul contrive / Against thy mother aught. Leave her to heaven / And to those thorns that in her bosom lodge / To prick and sting her" (1.5.84-88). 



In other words, no matter how young Hamlet chooses to accomplish his revenge on Claudius, his father wants him to leave his mother alone and not attempt to punish her for marrying so quickly after his father's death; in addition, Hamlet should not corrupt his own mind in the process of exacting revenge on Claudius. 


While Hamlet does successfully achieve his revenge on the new king, he disobeys his father's instructions in the other two respects.  He does punish his mother, blaming her and treating her harshly as a result of her overhasty remarriage, and he also corrupts his mind by delaying action against Claudius for various reasons.  Hamlet begins to consider himself a coward, becoming somewhat obsessed with death, and he even kills Polonius in a hasty rage.  

How does Browning catch the essence of an age through the words of a single character in "My Last Duchess?"

Within the 56 lines of his dramatic monologue, Browning exposes not only Duke Ferrara but also the age in which he lived. That age was a time when a large number of landed aristocrats ruled over their own small city-states in Renaissance Italy. The control these men asserted over their society is captured in the poem as Duke Ferrara displays the "power, art, sophistication, [and] pitiless tyranny" (Allingham) typical of the time. 


Ferrara shows his power, and therefore the power that such aristocrats wielded in his age, by referencing his hiring of the artists Fra Pandolf and Claus of Innsbruck to do his bidding. He also runs an estate which employs people, such as the "officious fool" who broke off a cherry bough for the Duchess, raising the Duke's ire. Keeping the Duchess' painting behind a curtain and only drawing it back personally is a metaphor for the power Ferrara exercises over the minutest details, and he also demonstrates his controlling nature by the way he treats the Count's envoy, saying, "Nay--we'll go together down, sir" when the envoy tries to leave before he receives permission. Here Ferrara pulls rank on the ambassador but also on the Count, who was of a lower level of aristocracy than a duke. Obviously the greatest example of the Duke's power is that he has been able to do away with his "last Duchess" without suffering any consequences.


The art that played such an important role in Renaissance culture is amply represented in the poem by the extended reference to Fra Pandolf's act of painting the portrait and by the Duke's deliberate pointing out of the sculpture he commissioned. The bronze statue of "Neptune taming a seahorse" is symbolic of the Duke's ability to dominate not only the artist, but also his wife and anyone else because of his own status that is god-like in his society.


Ferrara shows the sophistication of his age by giving the tour of his personal gallery and also by his elevated diction. Although he ironically claims to not have "skill in speech," his discussion of the dowry with the envoy uses pretentious language: "The Count your master's known munificence is ample warrant that no just pretense of mine for dowry will be disallowed." 


Finally, the "pitiless tyranny" that aristocrats were able to exercise, and historically did exercise in the 16th century, is made clear by the Duke's assertion that "I gave commands; then all smiles stopped together." 


Browning brilliantly captures not only the mindset of an individual man in "My Last Duchess," but also that of the Renaissance age in which the poem is set.

What are some of the disadvantages of the Igbo culture's social structure in Things Fall Apart?

In Chinua Achebe’s Things Fall Apart, one of the major disadvantages inherent with the traditional Igbo culture’s social structure can be found in the tribe’s treatment of undesirables and outcasts, or osu. Osu are unable to climb up the rungs of society in the same way that Okonkwo and others can; indeed, the Igbo of Umuofia enforce a kind of caste system:



"He was a person dedicated to a god, a thing set apart-- a taboo for ever, and his children after him. He could neither marry nor be married by the free-born. He was in fact an outcast, living in a special area of the village.... Wherever he went he carried with him the mark of his forbidden caste-- long, tangled and dirty hair. A razor was taboo to him. An osu could not attend an assembly of the free-born, and they, in turn, could not shelter under his roof. He could not take any of the four titles of the clan, and  when he died he was buried by his kind in the Evil Forest" (156).



The clan’s maltreatment of osu creates a powerful recruiting opportunity for the incipient Christian missionaries in the region, and they increase their numbers by incorporating osu into the church.


Another notable disadvantage in the Igbo’s social structure comes in the form of their strict punishment system. Okonkwo is himself a victim of a seemingly arbitrary sentence when he is exiled from Umuofia for seven years for inadvertently killing a young member of the tribe. Obierika questions these traditions after Okonkwo is punished:



“When the will of the goddess had been done, he sat down in his obi and mourned his friend's calamity. Why should a man suffer so grievously for an offense he had committed inadvertently? But although he thought for a long time he found no answer. He was merely led into greater complexities. He remembered his wife's twin children, whom he had thrown away. What crime had they committed? The Earth had decreed that they were an offense on the land and must be destroyed” (125).



Obierika questions how these traditions actively benefit the clan, especially when they seem to actually hurt those that surround him.


These are a few examples of how the rigid traditions of the Igbo culture can be problematic to members of the clan. Osu and Okonkwo alike suffer due to the social structures that are firmly upheld by the tribe in Umuofia.

The pivotal characters in the play are John and Elizabeth Proctor. How are they involved in these trials?

John and Elizabeth Proctor only become involved in the witch trials because of their past relationships with Abigail Williams, the niece of Reverend Parris, who makes the initial accusation against Tituba, Parris's slave, as well as the majority of the succeeding accusations.


Abigail used to work for the Proctors, helping out in their home and with their children. She and John began to have an affair, and when Elizabeth found out about it, she fired Abigail from their service. Abigail believes that John still has feelings for her. In Act One, she says, "I saw your face when she put me out, and you loved me then and you do now!" She blames Elizabeth for separating them and for making him keep his distance from her.  


In Act Two, we learn of Elizabeth's belief that Abigail "wants [her] dead." Mary Warren, their new employee, says that Elizabeth's name was "mentioned" in the court, but she assured the judges that she never saw any reason to suspect Elizabeth of witchcraft. Elizabeth now fears that Abigail will accuse her in order to get her out of the way; "She thinks to take my place, John," she says.


Elizabeth turns out to be right, as we learn at the end of this act. In Act Three, when John goes to the court to defend her, Mary Warren turns on him and he is accused too. This is how this couple becomes involved in the trials; it all began with John's affair with Abigail.

Monday, December 20, 2010

How does the story "The Interlopers" by Saki have suspense in it?

"The Interlopers" begins with suspense as "a man stood ... watching and listening," waiting for a "beast" to come within range of his rifle. The middle has suspense as Ulrich and Georg come "face to face." The crisis, leading to the story-end climax, has suspense as both men wait to see who it is who is coming to their aid.

Suspense weaves throughout the story because of Saki's deft structural development. Suspense is relieved--only to be heightened again--when the narrator describes the backstory centering around the court case over the illegally possessed land and again when Ulrich and Georg start talking after Ulrich offers Georg some wine from his flask (at first Georg retorts with hateful remarks but then he responds with talk from his heart: "if we choose to make peace ... [y]ou would come and keep the Sylvester night beneath my roof").

Saki heightens the suspense after this reconciliation between the two enemies by giving them and us the hope of a speedy and timely rescue. They and we believe they will live long lives of friendship and peace, feasting together at "Sylvester night" and at "some high day" (respectively, a Catholic Saint's Day coinciding with New Year's Eve on the Gregorian Calendar and any number of religious holy days for "Karpathians"). They call out together to what they believe to be one or the other set of their men approaching them, searching for the missing leaders: "They hear us! They've stopped. Now they see us." Suspense intensifies through the crisis to the climax as--after successfully raising their "voices in a prolonged hunting call"--Georg asks "How many are there? ... Are they your men? ... Are they your men?" His answer is Ulrich's "unstrung" hideously fearful "No."



     "They hear us! They've stopped. Now they see us. They're running down the hill towards us," cried Ulrich.
     "How many of them are there?" asked Georg.
     "I can't see distinctly," said Ulrich; "nine or ten,"
     "Then they are yours," said Georg; "I had only seven out with me."
     "They are making all the speed they can, brave lads," said Ulrich gladly.
     "Are they your men?" asked Georg. "Are they your men?" he repeated impatiently as Ulrich did not answer.
     "No," said Ulrich with a laugh, the idiotic chattering laugh of a man unstrung with hideous fear.


Sunday, December 19, 2010

When did Montag meet Faber in Fahrenheit 451? Please provide page numbers.

Montag met Faber in a park a year before the story started.


The first time Montag mentions Faber, it is very brief. He does not say who Faber is or what happened during the encounter that made it so memorable.



What a strange meeting on a strange night. He remembered nothing like it save one afternoon a year ago when he had met an old man in the park and they had talked... (Part I, p. 8)



This is very early in the book, so at this point the reader has no idea what Montag is talking about. He remembers the encounter with Faber when he is thinking about Clarisse. He clearly associates the two because both of them make him question himself, his profession, and his society.


We learn later that Montag saw Faber in the park, and also saw him quickly hide something. Montag stopped to talk to him, and eventually Faber let his guard down and they had a conversation.



The old man admitted to being a retired English professor who had been thrown out upon the world forty years ago when the last liberal arts college shut for lack of students and patronage. His name was Faber, and when he finally lost his fear of Montag, he talked in a cadenced voice, looking at the sky and the trees and the green park... (Part I, p. 70)



The meeting ends with Faber quoting “a rhymeless poem.”  Faber tells him that he talks “the meaning of things” and is alive. The meeting clearly made an impression on Montag. When he finally got up the nerve to look Faber up in order to further explore the world of books, Montag knew he was in very deep. Montag seeks him out because he himself can steal books, but is not really educated enough to read them.


Please note that editions of books vary. These page numbers are from the 2011 edition (ISBN 9781439142677).

When the following substances go from liquid to solid, which would require the lowest temperature for it to freeze? Ar, C6H12, HF, NaCI, Cu Why?...

The freezing point of a substance is related to the intermolecular forces that exist between the particles of a substance.


Intermolecular forces are the forces of attraction or repulsion that act between the particles of a substance. A particle can be composed of atoms, molecules, or ions. 


The different types of intermolecular forces are listed below from strongest to weakest:



  • Electrostatic forces: strong attraction between oppositely charged particles


  • Hydrogen bonding forces: attraction between the H atom of one molecule and the F, O, or N atom of another molecule


  • Dipole-dipole forces: attraction between polar molecules with an uneven charge distribution


  • London dispersion forces: attraction between nonpolar molecules 

The stronger the forces between the particles, the higher the freezing point. Therefore, the substance with the weakest intermolecular forces will have the lowest freezing point. The substance with the weakest intermolecular forces (London dispersion forces) and the lowest freezing point is argon (Ar)

In Tuck Everlasting, compare and contrast the Tucks' house and the Fosters'. Which does Winnie prefer?

The Tucks’ home is much more disorganized and comfortable than the Fosters' home, and Winnie is homesick. 


Winnie is surprised by the way the Tucks live.  She does not necessarily prefer the way the Fosters live, but she is not used to the way the Tucks live.  Everything is comfortable but a little bit haphazard and messy at the Tuck house. 


The Foster house is one where there is a place for everything and everything is in its place.  It is a household where it is the women’s duty to keep things neat.  Winnie has been trained to view housekeeping this way.



Winnie had grown up with order. She was used to it. Under the pitiless double assaults of her mother and grandmother, the cottage where she lived was always squeaking clean, mopped and swept and scoured into limp submission. There was no room for carelessness, no putting things off until later. (Ch. 10)



Therefore, she is totally unprepared for the kind of household she steps into at the Tucks’ house.  The Tucks believe more in comfort than in order.  Winnie is amazed and enamored of the “homely little house beside the pond.”  She finds it disorderly, but realizes the Tucks are okay with that.



It was a whole new idea to her that people could live in such disarray, but at the same time she was charmed. It was . . . comfortable. … "Maybe it's because they think they have forever to clean it up." And this was followed by another thought, far more revolutionary: "Maybe they just don't care!" (Ch. 10)



Dust, messes, and disorganization do not bother the Tucks.  They have lived long enough to get their priorities straight.  Apparently, when you live forever it no longer matters to you if the dishes are done or not.  Other things in life become more valued.


Although Winnie finds this lifestyle luxurious and exciting, she also misses home. She has never been away from home before, and never slept in a bed besides her own.  It is not a matter of choosing one lifestyle over another, at the point. Winnie just misses the familiar.


In the end, Winnie chooses not to become immortal.  She remains a Foster.  Winnie has learned some interesting lessons about life from the Tucks and her experiences with them, but she decides that she would rather continue being mortal and living her own life.

What is Haemophilus?


Pathogenicity and Clinical Significance


H. influenzae was named when it was isolated in the 1890’s from
persons suffering from influenza. It was later shown to be a
secondary bacterial infection and not the causative agent of that
disease. It is similar to many other members of this genus. In fact, H.
aegyptius
, which causes conjunctivitis and Brazilian purpuric
fever, has been reclassified as a subtype of H. influenzae rather
than a separate species. Natural infections occur only in humans, although
infection can be artificially induced in a few animal species.


Both encapsulated and nonencapsulated strains exist. The encapsulated strains
show higher degrees of pathogenicity, most likely because the
capsule offers some protection against the host’s immune system and possibly
increases the bacteria’s virulence. Encapsulated strains are
divided into six serotypes (a-f) with H. influenzae serotype B
(Hib) being the most common pathogenic group. Before the widespread use of Hib
vaccine, approximately 95 percent of all invasive Haemophilus
infections in children, including 75 percent of meningitis cases, and 50 percent
of Haemophilus infections in adults, were caused by Hib. Hib
commonly causes meningitis, pneumonia, bacteremia, cellulitis, epiglottitis, and
septic arthritis. It also can cause osteomyelitis and endocarditis. In developed
countries, Hib infections in children have markedly decreased since the early
1990’s, when the
Hib vaccine became widely used. In the United States, for
example, Hib infections in children decreased 99 percent between 1990 and
2000.


The percentage of infections caused by nonencapsulated H. influenzae (NTHi) has risen markedly since the introduction of the Hib vaccine. NTHi strains are present in the nasopharynx of 80 percent of the adult population and, because the strains lack capsules, are not affected by the vaccines that target capsular antigens. Migration of the NTHi bacteria from the nasopharynx can lead to otitis media (middle-ear infection), sinusitis, bronchitis, and pneumonia. Many of these infections are self-limiting because the immune system recognizes nonencapsulated strains more readily than those that are encapsulated. NTHi can also lead, more rarely, to disseminated systemic disease. Smoking, viral infections, chronic lung disease, and immunodeficiency can make NTHi infections much more likely. In 2006, NTHi accounted for almost two thirds of all H. influenzae infections in the United States.


Ampicillin has been the drug of choice for treating H. influenzae, but many strains have developed resistance to the penicillin family of antibiotics. Chloramphinicol has also been used, but chloramphenicol resistance is also on the rise. Second and third generation cephalosporins, fluoroquinolines, and clarithromycin are good alternatives. In severe cases, the cyclosporins cefotaxime and ceftriaxone can be administered intravenously.



H. ducreyi was first isolated in 1899. It is most commonly isolated from the urogenital mucosa of humans, the bacterium’s only natural host. Like most members of its genus, H. ducreyi is a fastidious bacterium that requires enriched chocolate agar for growth. Genetic testing of H. ducreyi has shown it to be genetically related (albeit distantly) to other Haemophilus spp. and even to other members of Pasteurellaceae, although it has nutritional requirements similar to other members of this family. Some bacteriologists have suggested that H. ducreyi be placed as a monotypic genus in its own family.



H. ducreyi infection leads to chancroid
(soft chancre), a common sexually transmitted disease in less developed countries
in tropical and subtropical regions. The disease causes ulceration of the
genitalia and is endemic to sub-Saharan Africa, especially among men who have sex
with sex workers, who often are reservoirs for H. ducreyi.
H. ducreyi infection increases the likelihood of
human
immunodeficiency virus (HIV) transmission ten to one hundred times. Chancroid is uncommon in
the United States, with the last major outbreak in the 1980’s. Azythomycin is the
drug of choice for treating H. ducreyi infections. Erythromycin,
ciprofloxacin, and in severe cases, ceftriaxone are also used.


Other Haemophilus spp. that are commensal in humans only
rarely cause opportunistic infections. H. haemolyticus,
H. parahaemolyticus, and H. parainfluenzae
are commonly found in the nasopharynx and oral cavities but are seen associated
only with pharyngitis and other conditions in debilitated persons. It
has been suggested that H. avium and H. agni be
placed within other genera in the Pasteurellaceae family because they are
genetically distant from all other Haemophilus spp. Other
species, such as H. paracuniculus and H.
parasuis
, are somewhat genetically closer to the
Haemophilus spp. that affect humans, but their taxonomy is
under scientific review.



Albritton, W. L. “Biology of Haemophilus ducreyi.” Microbiological Reviews 53 (1989): 377-389.


Garrity, George M., ed. The Proteobacteria. Vol. 2 in Bergey’s Manual of Systematic Bacteriology. 2d ed. New York: Springer, 2005.


Madigan, Michael T., and John M. Martinko. Brock Biology of Microorganisms. 12th ed. Upper Saddle River, N.J.: Pearson/Prentice Hall, 2010.


Spinola, Stanley M., Margaret E. Bauer, and Robert S. Munson, Jr. “Immunopathenogenesis of Haemophilus ducreyi Infection (Chancroid).” Infection and Immunity 70 (2002): 1667-1676.

Saturday, December 18, 2010

What is influenza vaccine?


Definition

The influenza vaccine helps to protect against infection with the influenza virus.
Influenza is an acute viral respiratory illness with abrupt
onset and is spread primarily by respiratory droplets from person to person
(mainly through inhalation of virus-containing droplets). Influenza is caused by a
group of viruses of the Orthomyxoviridae family, which are separated into three
strain types (A, B, and C) according to their nuclear material.




Vaccination is the most effective protection against influenza. It is recommended for unhealthy persons and for persons who are likely to transmit influenza to unhealthy persons in a given community. Moreover, the vaccine may be administered to anyone wishing to reduce the risk of influenza.



Influenza vaccines are designed to trigger an immune response to
hemagglutinin and neuraminidase, the two proteins found
on the surface of the influenza virus. These proteins are always changing
(mutating), so every year, seasonal influenza vaccines have to be reformulated
with the three strains that are likely to be more effective in fighting new
influenza strains.


The World
Health Organization’s Global Influenza Programme monitors the influenza viruses circulating
among humans worldwide and quickly identifies new strains so that new, appropriate
vaccines can be made for a particular year.




Types of Influenza Vaccines

The trivalent inactivated influenza vaccine (TIV) has been available since the mid-twentieth century. TIV is administered by intramuscular or intradermal routes and contains three inactivated viruses: type A (H1N1), type A (H3N2), and type B. The influenza vaccine viruses are grown in chicken egg, thus the final product contains residual egg protein. The vaccines are also available in both pediatric- and adult-dose formulations and can be preservative-free in a single vial or in a multidose vial with thimerosal as a preservative.


The live attenuated influenza vaccine (LAIV), which contains the same three influenza viruses as TIV, is administered by intranasal route. LAIV viruses are also grown in chicken egg. LAIV is preservative-free and is provided in a single-dose sprayer unit with one-half the dosage sprayed into each nostril.


Improved technology and innovation has enabled improved methods of administering influenza vaccines, including a reduced-dose injectable made possible by the addition of adjuvants, and the use of a cell culture vaccine. Scientists are also exploring new routes of administration, such as intradermal (with or without needle) and transcutaneous, in which a patch delivers the vaccine through micro-needles that may barely penetrate the skin before dissolving and releasing the vaccine.


Most vaccinated persons develop postvaccination hemagglutination inhibition
antibody titers. These antibodies are protective against
illness caused by strains similar to those in the vaccine or by related variants
that may emerge during outbreaks.


Amidst debates over the effectiveness and necessity of vaccinations, concern had also always existed over the high number of elderly adults who would still succumb to influenza and possibly lose their lives despite having been vaccinated because of their naturally weaker immune systems. Therefore, in late 2015, the US Food and Drug Administration (FDA) approved an influenza vaccine booster that had previously been in use in several other countries. The vaccine with the adjuvant, which helps stimulate the immune system to make the vaccine more effective, is known as Fluad and was expected to be available in the United States in 2016. Additionally, scientists were continuing to experiment on whether a universal vaccine could be produced that would help the immune system fight groups of viruses rather than a specific strain.




Bibliography


Betts, R. F. “Influenza Virus.” In Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases. Ed. Gerald L. Mandell, John E. Bennett, and Raphael Dolin. 7th ed. New York: Churchill, 2010. Print.



Delves, Peter J., et al. Roitt’s Essential Immunology. 11th ed. Malden: Blackwell, 2006. Print.



Fox, Maggie. "Fluad: Food and Drug Administration Approves a New, Boosted Flu Vaccine." NBC News. NBCNews.com, 30 Nov. 2015. Web. 30 Dec. 2015.



Hak, E., et al. “Influence of High-Risk Medical Conditions on the Effectiveness of Influenza Vaccination Among Elderly Members of Three Large Managed-Care Organizations.” Clinical Infectious Diseases 35 (2002): 370–77. Print.



Plotkin, Stanley A., Walter A. Orenstein, and Paul A. Offit. Vaccines. 5th ed. Philadelphia: Saunders, 2008. Print.



Zhang, Sarah. "Scientists Get One Step Closer to a Universal Flu Vaccine." Wired. Condé Nast, 24 Aug. 2015. Web. 30 Dec. 2015.

How does the choice of details set the tone of the sermon?

Edwards is remembered for his choice of details, particularly in this classic sermon. His goal was not to tell people about his beliefs; he ...