St Jude Children's Research Hospital is a non-profit organization. What does their Activity Statement, aka the income statement, say?

If I am interpreting your question correctly, it seems that you want to know whether the annual report put out by St. Jude’s indicates that it is truly a non-profit organization. There are a couple of things about St. Jude’s that are a little bit unique, as non-profit organizations go. First is that its expense budget is very large, due to the fact that it is a medical research and treatment center. Second is that since part of St. Jude’s mission is to try to find cures for serious childhood diseases, any income above what is required for the hospital to continue serving children at no cost to their families is then applied to that mission. 

Their annual report for the 2014 fiscal year indicates that their net revenue was $1,586,578,000 and their net expenses were $997,401,000. This appears to show a “profit” of $587,488,000. In reality, their business model utilizes every donation and endowment for the purpose of treating childhood diseases and searching for a cure for them. So although their net assets have increased over the course of the year, these assets are applied to continuing research and other costs for the purpose of St. Jude’s mission. It is also notable that an organization like St. Jude’s cannot be sustained “living paycheck to paycheck” so to speak. The revenue that appears to be extra is more like a buffer to ensure that their doors stay open. Many of their employees and board members are volunteers, and although it seems that they take good care of their employees, there are by no means unreasonably large salaries being given to a small number of executives. St. Jude’s continues to meet the government requirements for a 501(c)3 non-profit organization.