Vitamin E
Effect: May Protect Against Side Effects
One of the problems with amiodarone is that it can cause injury to the
lungs. One study suggests that vitamin E
supplements might help prevent this side effect.
Chaparral, Comfrey, and Coltsfoot
Effect: Possible Harmful Interaction
The herbs chaparral (Larrea tridentata or L.
mexicana), comfrey (Symphytum officinale), and
coltsfoot (Tussilago farfara) contain liver-toxic substances.
Because amiodarone can also affect the liver, combining these herbs with the
medication is not advisable.
Dong Quai, St. John’s Wort
Effect: Possible Harmful Interaction
Amiodarone has been reported to cause increased sensitivity to the sun,
amplifying the risk of sunburn or skin rash. Because St.
John’s wort and dong quai may also cause this problem, taking these herbal
supplements during amiodarone therapy might add to this risk. It may be a good
idea to use sunscreen or wear protective clothing during sun exposure if taking
one of these herbs while using amiodarone.
Bibliography
Kachel, D. L., et al. “Amiodarone-Induced Injury of Human Pulmonary Artery Endothelial Cells: Protection by Alpha-Tocopherol.” Journal of Pharmacology and Experimental Therapeutics 254 (1990): 1107-1112.
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